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KMID : 0604020090240010028
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Korean Journal of Critical Care Medicine
2009 Volume.24 No. 1 p.28 ~ p.32
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The Characteristics and Prognostic Factors of Severe Sepsis in Patients Who Were Admitted to a Medical Intensive Care Unit of a Tertiary Hospital
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Hong Soo-Jung
Hong Sang-Bum
Lim Chae-Man
Koh Youn-Suck
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Abstract
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Background: Severe sepsis is a major cause of morbidity and mortality in intensive care units. This study aimed to evaluate the prevalence, characteristics, outcomes and prognostic factors of severe sepsis in a medical intensive care unit (MICU) of a tertiary care hospital in Korea.
Methods: We retrospectively reviewed the medical chart of 249 patients who were admitted to a medical intensive care unit with severe sepsis.
Results: From January 2000 to December 2001, 3410 patients were admitted to the ICU. The prevalence of severe sepsis was 7.3%. The mortality of severe sepsis was 64.6%. The prognostic factors for severe sepsis were the number of organ systems that acutely failed (p=0.036) and an admission route from general wards (p=0.018). There was no difference in the outcome of severe sepsis according to infectious organisms (p=0.24) and the site of infections (p=0.38).
Conclusions: Severe sepsis in the MICU is a common, expensive and often fatal condition. We expect that early rescucitation and recovery from acute organ system failure will improve the outcome of severe sepsis.
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KEYWORD
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infection, organ failure, severe sepsis
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